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The London Pharmaclinic

Weight Loss Journey: Step-by-Step Explanation?

Your Weight Loss Journey In 3 Simple Steps.

  • Free Consultation & Assessment. Face-to-Face or Virtually.
  • Personalised Prescriber-Led Plan
  • Achieve Lasting Weight Loss & Prescriber Support.

Help, I’m scared of needles! – Don’t worry, we can even do the injections for you in our London clinic.

How does it work?

What is Mounjaro and How Does It Work?

Mounjaro is a cutting-edge weight loss and diabetes medication that helps regulate blood sugar and curb hunger. It works by mimicking natural hormones in the body that control appetite, digestion, and energy use. This dual-action approach helps reduce cravings, improve blood sugar levels, and boost metabolism, making it easier to lose weight and maintain long-term health.

Key Benefits of Mounjaro:
Supports weight loss by reducing hunger and cravings
Helps manage blood sugar levels for people with type 2 diabetes
Boosts metabolism for better energy use
Encourages long-term weight management

Mounjaro is becoming a popular choice for weight loss and diabetes management in the UK. If you’re looking for an effective way to control appetite and improve overall health, speak to our healthcare provider to see if Mounjaro is right for you.

Mounjaro can help reduce your appetite, help fight cravings, reduce food noise and slow gut motility helping you eat less. In other words, Mounjaro helps you feel full faster and for longer allowing you to kickstart your weight loss and make your weight loss journey easier.

For maximum results, it’s recommended that Mounjaro is used with a balanced calorie-conscious diet and increased regular exercise.

Why Mounjaro?

Mounjaro is available in a range of doses which makes it the most bespoke of all the weight loss drugs.

Your London Pharmaclinic prescriber practitioner will assess your personal needs based on your weight and medical history and prescribe an appropriate starter dose for you. It’s important that a medical expert considers any regular medications you may be on.

As your weight loss journey progresses, your clinical prescriber can carefully titrate your dose to the maximum dose for you in terms of effectiveness and tolerability. Doses are usually titrated upwards on a 4-weekly basis until you reach the most suitable dose for you.

The safety of this titration journey is a critical part of your journey.

Clinical Effectiveness

Mounjaro (Tirzepatide) is an innovative medicine developed to manage and support weight loss. It was developed to manage type 2 diabetes. It is a dual action GIP and GLP-1 receptor agonist. This means it targets two key pathways in the body to enhance blood sugar control and support weight loss.

This dual-action mechanism distinguishes it from other GLP-1 receptor agonists like Semaglutide (known as Wegovy or Ozempic) or Liraglutide (Victoza).

But how effective is it in real-world and clinical setting? Let’s explore the evidence.

Clinical Trials and Outcomes

The SURMOUNT-1 Clinical Trials (Patients Overweight/Obese Without Diabetes).

This landmark trial evaluated Mounjaro exclusively for weight loss in non-diabetic individuals with a BMI> 30 or >27 (with comorbidities). After 72 weeks:

  • 5mg dose produced an average of 15% weight loss
  • 10mg dose produced an average of 19.5% weight loss
  • 15mg dose produced an average of 20.9% weight loss

Over 50% of participants on the 15mg dose lost at least 20% of their body weight, bringing the outcomes close to those typically seen in bariatric surgery.

Comparative Data

Weight loss with Mounjaro at higher doses (15mg) outperforms existing GLP-1 receptor agonists, such as:

  • Semaglutide 2.4mg (Wegovy) averaged 15-17% weight loss
  • Liraglutide (Saxenda) averaged 5-8% weight loss

Real-World Context

In clinical practice, these findings translate to significant benefits for individuals with obesity or weight-related conditions like diabetes, hypertension (high Blood Pressure), or cardiovascular risks. The dual action mechanism (GIP + GLP-1 receptor agonism) play a key role in this dramatic weight loss effect by reducing appetite and improving metabolic efficiency.

The SURPASS Trials. (Patients Overweight/Obese WITH Diabetes)

The effectiveness of Mounjaro has been rigorously evaluated through the SURPASS clinical trial program which demonstrated the following outcomes.

Weight Loss.

Patients lost up to 22% of their body weight over 72 weeks, making it one of the most effective treatments for weight loss among diabetes medication

Blood Sugar Control.

Mounjaro significantly reduces HbA1c levels (a marker for long term blood sugar control), with many patients achieving Hb1Ac levels below 7% (the goal for most diabetics). In head-to-head trials, Mounjaro outperformed Semaglutide in lowering HbA1c.

Mounjaro not only improved glycemic control but also showed greater weight loss than soe leading competitors in its class, offering added value for individuals struggling with obesity-related diabetes.

Mounjaro stands out for its dual-action mechanism, significant glycemic control, and weight-loss benefits. Its performance in clinical trialssugests it is a highly effective option for managing type 2 diabetes, especially for those who are also overweight.

Storage

Mounjaro pens should be stored in a refrigerator where they should last until their expiry date. If taken out of a refrigerator, for example if you are going on holiday, they will still be safe to use at room temperature (up to 30degress C) for 30 days after first use.

Ingredients

The Mounjaro weight loss injection contains additional excipients such as Disodium phosphate dihydrate, Propylene glycol, Phenol, Hydrochloric acid (for pH adjustment), Sodium hydroxide (for pH adjustment), and water for injection.

Possible side effects and how to manage them

As with all injectable weight loss medication, some side effects may occur. At London Pharmaclinic we have chosen to prescribe Mounjaro because we believe it to have the least amount of potential side effects combined with the greatest success levels.

Side effects may include headache, nausea, diarrhoea, constipation, abdominal discomfort, fatigue, weakness – these effects usually settle in time and we monitor them carefully to ensure you are on the correct dosage for you as an individual.

Avoiding high sugar or high fat foods, eating smaller portions can help you manage these possible side effects. Drinking plenty of fluids is also important as weight loss medications can also supress your desire to drink liquids.

If you experience long-term or more significant side effects, contact London Pharmaclinic for advice or speak to your GP.

For a complete list of possible side-effects read the patient information leaflet provided with your medication.

How long will I be on Mounjaro?

Effective, long-term weight loss is a journey. Although you may experience immediate gratifying results, it will take time to reach your desired goal. Mounjaro is a tool to help you achieve that goal. Typical patients will use Mounjaro for at least 12 months but our team will tailor your journey to your specific needs.

Research shows that once you stop taking weight-loss medication, weight can creep back on. It’s the medication which helps you control your appetite therefore it’s important that you aim to change your relationship with food and build healthier eating habits for when you stop taking Mounjaro.

For maximum results, it’s recommended that Mounjaro is used with a balanced calorie-conscious diet and increased regular exercise.

Can I switch from Wegovy or Ozempic to Mounjaro?

At London Pharmaclinic we usually advise a 1-month period for switching between medications but we can tailor our advice to your needs depending on your dosage and the length of time you’ve been on the medication. Get in touch to discuss your best option.

Who is Mounjaro not suitable for?

Do not use Mounjaro weight loss injections if:

  • You are under 18
  • 
You or any of your family have ever had medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).
You are allergic to tripeptide or other ingredients in Mounjaro
  • You are pregnant or breastfeeding – Mounjaro is not suitable for anyone pregnant or planning pregnancy. You must leave a gap of at least 2 months between trying for pregnancy and using weight loss injections.

Consult your doctor if you have:

  • Medical conditions related to your pancreas or kidneys.
  • Type 2 diabetes or diabetic retinopathy in the past.
  • Diagnosed with mental health issues or eating disorders.

You should only buy Mounjaro online in the UK from reputable regulated pharmacies licensed by the General Pharmaceutical Council and registered with the Medicines Health Regulatory Authority to ensure the authenticity of your weight loss treatment.

Start your weight loss journey with The London PharmaClinic...